Tris(hydroxymethyl)aminomethane (TRIS / Trometamol / THAM, CAS 77-86-1) is white crystalline powder. It is a classic biological buffer with pKa ~8.1 at 25℃, widely used in biochemistry, molecular biology, diagnostic reagents and pharmaceutical excipients. TNJ Chemical is the leading manufacturer and exporter since 2001 from China. We guarantee high quality, competitive price, stable supply, fast delivery and tech support etc. To inquire more, please contact sales@tnjchem.com
Product Information
CAS No.: 77-86-1
Name: Tris(hydroxymethyl)aminomethane
Synonym: Tris Base, Tromethamine, THAM, 2-Amino-2-(hydroxymethyl)-1,3-propanediol
EC No.: 201-064-4
Molecular Formula: C₄H₁₁NO₃
Molecular Weight: 121.14
MDL: MFCD00004679
Chemphysical Properties
Appearance: White crystalline powder
Melting point: 168–171 ℃
Solubility: Freely soluble in water, soluble in ethanol; slightly soluble in ethyl acetate
Buffer range: pH 7.0–9.0
Stability: Stable at room temperature; pH value of Tris solution is temperature-dependent
Quality Specification
| Item | Standard |
|---|---|
| Assay (HPLC) | 99.5% min / 99.9% min |
| Loss on drying | 0.30% max |
| Residue on ignition | 0.05% max |
| Heavy metals (Pb) | 5 ppm max |
| Melting range | 168–171 ℃ |
Use & Application
Biochemical & molecular biology: Prepare TAE, TBE, TE buffer for electrophoresis, protein and nucleic acid experiments
Diagnostic & in-vitro reagents: Buffer component for ELISA, biochemical test kits
Pharmaceutical: Trometamol raw material, pH regulator and excipient
Analytical chemistry: Primary standard for acid titration
Fine chemical: Intermediate for surfactants, curing agents and polymer additives
Packing
25kg fiber drum with PE inner bag.
Delivery & Storage
Seal tightly, store in cool, dry and ventilated warehouse, protect from moisture. Non-hazardous.
chemical.tnj
+8618949823763
tnjchem
2881500864