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Chlorpheniramine maleate (CAS No 113-92-8), is a first-generation alkylamine antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorphenamine is one of the most commonly used antihistamines in small-animal veterinary practice. Although not generally approved as an antidepressant or anti-anxiety medication, chlorphenamine appears to have these properties as well.
Specification
Appearance White crystalline powder
Solubility Freely soluble in water and ethanol
Identification
A: Melting point, ℃ 130.0~135.0
B: IR absorption Complies to standard
C: Optical rotation -0.10o~+0.10o
Color of solution Clear and not more intensely than BY6
Related substance, %
Impurity A ≤0.20
Impurity B ≤0.10
Impurity C ≤0.10
Impurity D ≤0.10
Any other single impurity ≤0.10
Total impurity ≤0.10
Heavy metals, ppm ≤20.00
Loss on Drying, % ≤0.50
Sulfated ash, % ≤0.10
Assay, % 98.0~101.0
Application
1.Allergic rhinitis: allergic rhinitis and upper respiratory tract infection caused by nasal congestion effectively Cold or sinusitis
2.Skin and mucous allergies: the hives, hay fever, vasomotor rhinitis
3.Alleviate the itching and swelling caused by insect bites
4.Control drug eruption and contact dermatitis
Packaging&Storage
25 kg/drum.
Stored in dry and ventilation place, far from heat and water.
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